RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
RASAL1
RNA ID
RNA Type
mRNA
Alteration Pattern
methylation
Species
homo sapiens
Detection Methods
CHIP; dual-luciferase reporter assay etc.
Target
NA
Pathway
NA
PubMed ID
Title
Epigenetic balance of aberrant Rasal1 promoter methylation and hydroxymethylation regulates cardiacfibrosis.
Year
2015
Function
Transcriptional suppression of rasal1 through aberrant promoter methylation contributes to endothelial-to-mesenchymal transition (EndMT) and ultimately to progression of cardiac fibrosis.